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TDOMF ERROR: Headers have already been sent in file /var/www/vhost/sidalava.org/home/html/wp-content/plugins/buddypress/bp-core.php on line 38 before session_start() could be called. This may be due to...

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Inicio > Noticias > VIH > Cuba probará este año una…

Cuba probará este año una vacuna contra el Sida en seropositivos

Fecha: 07/03/2012

Fuente: La Vanguardia

http://www.lavanguardia.com/salud/20120307/54265238064/cuba-probara-seropositivos-ensayo-vacuna-sida.html

El proyecto está “listo” para entrar en la “fase 1″ tras realizar las primeras investigaciones con ratones que resultaron positivas

Cuba iniciará este año las pruebas clínicas de un ensayo de vacuna contra el VIH-Sida en humanos seropositivos, tras realizar investigaciones con ratones que resultaron positivas, dijo hoy a Efe el responsable del proyecto, Enrique Iglesias.

“Se trata de un candidato vacunal basado en una hipótesis en la que buscamos una respuesta inmune del organismo que pueda generar protección contra el virus del Sida”, indicó el microbiólogo cubano durante un receso del Congreso Internacional “Biotecnología Habana 2012″.

Explicó que el producto denominado TERAVAC-VIH-1 tiene tres proteínas, una de ellas obtenida por ingeniería genética, y pretende lograr una respuesta celular contra el virus, que destruyan las células infectadas.

El proyecto está “listo” para entrar en la “fase 1″, según dijo el científico que la calificó de “muy primaria” con la advertencia de que “no se quieren generar falsas expectativas” sobre su posible efectividad terapéutica, si bien ese es un extremo aún por comprobar con ensayos futuros.

En las investigaciones de esa vacuna participan biólogos, médicos y especialistas del Centro de Ingeniería Genética y Biotecnología (CIGB) y el Instituto de Medicina Tropical Pedro Kourí (IPK), de La Habana, rectores del proyecto.

El experto Iglesias subrayó que el equipo de investigación es consciente de que tiene dos retos fundamentales, uno de ellos que “no existe un modelo animal que reproduzca la enfermedad tal cual ocurre en humanos” y que es un estudio de “seguridad”.

“Este es el primer ensayo que realizamos en humanos, está dirigido a buscar seguridad, a observar si tras su aplicación se producen reacciones secundarias como fiebre, inflamación en la zona de inoculación o dolores de cabeza” y recalcó la recomendación expresa de “mantener la prevención” pues aún tenemos “un largo camino por recorrer”.

También precisó que hasta ahora han utilizado ratones en sus estudios y adelantó que la prueba en humanos incluirá a un grupo de 26 seropositivos, personas infectadas con el virus pero no enfermas, y dispuestas voluntariamente a participar.

El VIH-Sida tiene una prevalencia en Cuba de 0,19 por ciento, y desde 1986 se han detectado 15.824 casos, según datos citados por medios oficiales.

El Congreso de Biotecnología está dedicado al tema de las aplicaciones biomédicas y desarrollará hasta el próximo jueves 8 una agenda en la que Cuba expone también proyectos de vacunas contra el dengue y la hepatitis B, y productos terapéuticos para el tratamiento del cáncer de próstata y cérvico-uterino.

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